Matrix Science Pharma (MSP)

Evaluation of Herbicidal Properties of Mikania (Mikania Micrantha H.B.K) and Rain Tree (Samanea Saman Jacq Merr) Leaf Extract

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February 19, 2026 In Uncategorized

msp.04.2021.89.95

EVALUATION OF HERBICIDAL PROPERTIES OF MIKANIA (MIKANIA MICRANTHA H.B.K) AND RAIN TREE (SAMANEA SAMAN JACQ MERR) LEAF EXTRACT

Journal: Matrix Science Pharma (MSP)
Md. Shariful Islam, Muslima Khatun, Md. Nizam Uddin, Md. Sharifur Rahman, Shah Md. Ashraful Islam Md. Khaled Saifullah

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited

DOI: 10.4103/MTSP..MTSP_2_22

ABSTRACT

Weeds cause tremendous loss in crop yield and quality. In crop fields, weeds are one of the main pests reducing crop yield from 15% to 96%. In Bangladesh, weeds in crop fields are mainly controlled using labor. However, scarcity of agricultural laborers increases due to rapid industrialization. Hence, it is necessary to find out alternative ways to control weeds. One alternative is to use chemical herbicides which give rise to environmental hazards. Another option is to use of instrument to uproot weeds, but this is also difficult due to small size of land to apply different farm mechanization technology. Botanical herbicides have also been found to control weeds through utilizing the allelopathic potentials of these materials.

Pages 89-95
Year 2021
Issue 4
Volume 5

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February 19, 2026 In Uncategorized

msp.04.2021.84.88

A CASE STUDY OF MEDICINAL PLANTS AND THEIR USES BY THE SUNDAR HARAICHA NAGARPALIKA COMMUNITY IN MORANG DISTRICT, EAST NEPAL

Journal: Matrix Science Pharma (MSP)
Honey Raj Mandal, Shambhu Katel, Shulov Baidhya, Sujata Kattel, Amrit Katuwal

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited

DOI: 10.4103/MTSP..MTSP_1_22

ABSTRACT

Nepal offers a wide range of meteorological and geographical conditions. As a result, it has a high floral richness, with over 6500 flowering plants and ferns, 2000 of which are regularly employed in traditional. Nepal is ranked 9th in terms of floral diversity. People mostly use medicinal plants and other natural products for their chemical and pharmacological properties. Medicinal plants played an essential part in agronomy and pharmacy throughout the 18th and 19th centuries since they provided raw materials for the pharmaceutical industry and were used as a medicine on a daily basis. People mostly use medicinal plants and other natural products for their chemical and pharmacological properties.

Pages 84-88
Year 2021
Issue 4
Volume 5

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February 19, 2026 In Uncategorized

msp.04.2021.77.83

CHEMICAL CONTENTS IN RELATION TO THE ANTIMICROBIAL EFFICACIES OF SOLANUM SPP. SECT. PETOTA

Journal: Matrix Science Pharma (MSP)
Adeyinka A. Aladesida, Adeyinka O. Adepoju, Bunmi Adesola‑Famade, Temitope Olushola Ajiboye, Tolulope A. Fagbolu

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited

DOI: 10.4103/MTSP..MTSP_12_21

ABSTRACT

Since antiquity, plants have been employed not just as a source of food, clothing, and shelter but also for therapeutic use in traditional medicine. Over 1340 plants with defined antimicrobial activities are said to exist and over 30,000 antimicrobial compounds have been isolated from plants.[1,2] Plants which are used for therapeutic purposes are referred to as medicinal plants. Different parts of medicinal plants such as leaves, roots, rhizomes, stems, barks, flowers, fruits, grains, or seeds have been used to prevent and treat ailments; ranging from respiratory illnesses, urinary tract infection, gastrointestinal system illness as well as skin infections.[

Pages 77-83
Year 2021
Issue 4
Volume 5

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February 19, 2026 In Uncategorized

msp.03.2021.68.76

EXTRA VIRGIN OLIVE OIL NANOEMULSION ATTENUATED INFLAMMATORY RESPONSE IN LIPOPOLYSACCHARIDE‑INDUCED SEPSIS

Journal: Matrix Science Pharma (MSP)
Anna Surgean Veterini, Nancy Margarita Rehatta, Subijanto Marto Soedarmo, Heni Rachmawati, Widjiati, Widodo Jatim Pudjirahardjo, Annis Catur Adi, I Ketut Sudiana

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited

DOI: 10.4103/MTSP..MTSP_11_21

ABSTRACT

The provision of nutritional components in critical illness such as sepsis remains a big issue in clinical application, particularly through oral route due to intestinal integrity damaged‑associated absorption problem. The aim of this research was to develop Extra Virgin Olive Oil (EVOO) nanoemulsion as a nutrient carrier to improve its permeability while maintaining the intestinal mucosa integrity in mouse model of lipopolysaccharide‑induced sepsis. EVOO nanoemulsion was prepared by using ultrasonication‑mild agitation method. EVOO nanoemulsion (1.5 mL) was administered to the mice through orogastric tube. The effect of EVOO nanoemulsion was evaluated by assessing the histopathological alterations in lung, measuring the activation of NFκB‑p65 by immunohistochemistry of lung tissue, the levels of circulating Surfactant Protein‑D (SP‑D), tumor necrosis factor‑alpha, interleukin (IL)‑8, and IL‑10. The main result, EVOO nanoemulsion decreased circulating SP‑D level after 24 h. In conclusion, EVOO nanoemulsion is a promising carrier to improve nutrition absorption and decrease circulating SP‑D as organ injury biomarker.

Pages 68-76
Year 2021
Issue 3
Volume 5

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February 19, 2026 In Uncategorized

msp.03.2021.54.59

TINOSPORA CORDIFOLIA: A MULTIPURPOSE MIRACLE PLANT HAVING MEDICINAL IMPORTANCE: A REVIEW

Journal: Matrix Science Pharma (MSP)
Santoshi Malla, Lal Bista

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited

DOI: 10.4103/MTSP..MTSP_3_21

ABSTRACT

Medicinal plants are of great importance since the beginning of human civilizations. Popularity of medicinal plants is increasing year by year in plant‑based medicines, health products, pharmaceuticals, cosmetics, food supplements, etc., due to its well‑known properties along with its no side effects as compared to drugs. Tinospora cordifolia is commonly known as “Guduchi,” “Gurjo,” heart‑leaved moonseed,” or giloy. A chemical constituent present in various parts of T. cordifolia, their medicinal importance has risen up its popularity. Recently from the period of COVID‑19 pandemics, it is widely used to boost up immunity to fight against the coronavirus. This miracle plant is a shrub of vast Ayurvedic importance and is widely used in clinical research. This article had compiled diverse information regarding the identifications, chemical components present, pharmacological as well as Ayurvedic importance of T. cordifolia with a focus of it on recent occurred COVID pandemic as well

Pages 54-59
Year 2021
Issue 3
Volume 5

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February 19, 2026 In Uncategorized

msp.03.2021.60.67

ECOFRIENDLY ALTERNATIVES TO ANTIBIOTICS FOR IMPROVING GROWTH PERFORMANCE IN POULTRY

Journal: Matrix Science Pharma (MSP)
Ishwari Gyawali, Ramjee Paudel, Kailash Rayamajhi, Imtiyaz Ahmad Khan, Ghanashyam Dahal

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited

DOI: 10.4103/MTSP..MTSP_14_20

ABSTRACT

Over more than six decades, dietary antibodies are used not solely to regulate infectious disease but conjointly to improve growth performance and feed potency. They are accountable for building the immunocompetence of poultry against several
infectious diseases. However, the use of antibiotics as feed additives, in the long run, can lead to the development of bacteria resistant to drugs that are used to treat infections. Later on, they are of potential risk if they are transferred to humans. In‑feed antibiotic (IFA) has played a substantial role in the advancement and prosperity of the poultry industry since its discovery. When antibiotic is administrated, it impacts the entire population of the body. Among the bacteria, some are susceptible to the antibiotics that die, but some bacteria may thrive, and they begin to multiply. Sometimes, these remaining bacteria are resistant to many antibiotics, and many large problems can develop. There exist significant concerns about the use of an IFA, which leads to the development of antimicrobial resistance, creating a potential menace to human health.

Pages 60-67
Year 2021
Issue 3
Volume 5

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February 19, 2026 In Uncategorized

msp.03.2021.49.53

SOMATIC CELL COUNT: AN INDICATOR OF INTRAMAMMARY INFECTION IN DAIRY ANIMALS

Journal: Matrix Science Pharma (MSP)
Shankar Prasad Poudel, Reecha Acharya, Dipesh Kumar Chetri

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited

DOI: 10.4103/MTSP..MTSP_4_21

ABSTRACT

Mastitis, result of intramammary infections, exhibits serious economic problem in dairy sector due to the loss in milk yield and quality. Clinical and subclinical occurrence are common where subclinical cases are asymptomatic and need additional diagnostic tools for identification. Somatic cell counts (SCCs) in raw milk are an indicator for intramammary Intra-mammary infections (IMI) infections and thus helpful in subclinical mastitis forecasting. Somatic cells of 100,000 cells per ml are regarded as normal for uninfected milk and elevation above 200,000 cells per ml suspects IMI in cattle. The Somatic cell count (SCC) can be estimated with direct microscopic method or by flow cytometry. The major concerns of higher SCC are due to the hazardous effect on milk yield, milk quality, products processing, and pathogens that may have zoonotic importance. Good hygienic practices in shed and supplementations in rations can lower SCC and reduction of IMI. The regular monitoring of SCC is the pathway for early prediction of subclinical cases and assessing udder health management techniques for beneficent dairy business.

Pages 49-53
Year 2021
Issue 3
Volume 5

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February 19, 2026 In Uncategorized

msp.02.2021.42.48

BIOACTIVITIES OF ISOLATED PHYTOCHEMICALS AND EXTRACTS OF ABIES SPECTABILIS (D.DON) MIRB.

Journal: Matrix Science Pharma (MSP)
Vivek Saravanan

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited

DOI: 10.4103/MTSP..MTSP_6_21

ABSTRACT

Abies spectabilis (D.Don) Mirb. (synonyms: Abies brevifolia [A.Henry] Dallim.; Pinustinctoria Wall. ex D.Don; Abies chilrowensis Parl.; Pinusstriata Buch.‑Ham. ex Gordon and Glend.; A. spectabilis subsp. langtangensis [Silba] Silba; Pinus spectabilis D. Don; A. spectabilis var. langtangensis Silba; Picea webbiana [Wall. ex D.Don] Loudon; Abies webbiana [Wall. ex D.Don] Lindl.; and Picea naphta Knight) is a tree that belongs to the Pinaceae family. It grows up to 30 m tall in forests situated at an elevation from 2450 to 4000 m. Moreover, A. spectabilis is called தாளிசபத்திரி (Thaalisapaththiri) in Tamil/Siddha Medicine; Dhaatriparni, Dhaatripatra, Patraadhya, Taalisa, Taalisapatra, and Taalisha in Ayurveda; Taalisapattar in Unani; and Himalayan fir and Webb fir in English. This plant species is native to Asia (India, Afghanistan, Pakistan, and Nepal). This plant species has been categorized as near threatened by the International Union for Conservation of Nature and Natural Resources red list of threatened species.

Pages 42-48
Year 2021
Issue 2
Volume 5

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February 19, 2026 In Uncategorized

msp.02.2021.36.41

ABUSE AND MISUSE OF TRAMADOL AMONG THE YOUTH IN HODAN DISTRICT MOGADISHU SOMALIA

Journal: Matrix Science Pharma (MSP)
Abdikadir Ahmed Omar, Hassan Mohamed Ahmed

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited

DOI: 10.4103/MTSP..MTSP_5_21

ABSTRACT

Tramadol is a synthetic (manmade) pain reliever (analgesic) Researchers and doctors do not know the exact mechanism of action of tramadol, but it is similar to morphine. Like morphine, tramadol binds to receptors in the brain (narcotic or opioid receptors) that are important for transmitting the sensation of pain from throughout the body to the brain.

Pages 36-41
Year 2021
Issue 2
Volume 5

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February 19, 2026 In Uncategorized

msp.02.2021.23.35

POSSIBLE PHARMACOLOGICAL AND NONPHARMACOLOGICAL TREATMENTS FOR DIABETIC POLYNEUROPATHY

Journal: Matrix Science Pharma (MSP)
Sidra Munir

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited

DOI: 10.4103/MTSP..MTSP_3_21

ABSTRACT

Of the various types of micro‑ and macrocomplications associated with diabetes, the most common and serious complication is the nerve damage characterized by numbness
in hands and feet, effecting the proper functioning of organs such as kidney and heart to complete paralysis of body. These series of neurological conditions are referred to as diabetic neuropathy (DN). There are four most common types of DN, namely peripheral neuropathy (PN) also known as distal neuropathy, autonomous neuropathy (AN), proximal neuropathy also called as diabetic amyotrophy or radiculoplexus neuropathy, and mononeuropathy (MN) also called as focal neuropathy. There are other types of DN, which are less common, such as chronic sensorimotor Distal Polyneuropathy (DPN) and amyotrophic neuropathy

Pages 23-35
Year 2021
Issue 2
Volume 5

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