Matrix Science Pharma (MSP)

Paraquat Tongue

msp.02.2025.81

PARAQUAT TONGUE

Journal: Matrix Science Pharma (MSP)
Letter to Editor

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited

DOI: 10.4103/mtsp.mtsp_21_24_1

ABSTRACT

A 20-year-old male was admitted to our critical care unit, after several hours of suicide by ingesting between 10 and 20 ml of paraquat. His main symptoms were nausea and headache. Basic laboratory investigations were normal except for prolonged INR which was corrected over the next few days. An endoscopy of the upper gastrointestinal tract was positive for esophagitis. The tongue was coated with granulation from erosion as shown in the image

 

Pages 81
Year 2025
Issue 2
Volume 9

Download

Posted by Basem

msp.02.2025.75.80

PREVALENCE OF PREECLAMPSIA AND ASSOCIATED BIOMARKERS IN PREGNANT WOMEN IN AUCHI

Journal: Matrix Science Pharma (MSP)
Mahmud Mahmud, Olulope Olufemi Ajayi, Anthony Moses Ugbenyen

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited

DOI: 10.4103/mtsp.mtsp_28_24_1

ABSTRACT

Background: Preeclampsia is a multi-organ system disorder of pregnancy which is responsible for a significant rate of maternal morbidity and mortality worldwide. Studies on the prevalence of preeclampsia in the developing countries appear inadequate. Aim and Objective: This study was designed to assess the prevalence of preeclampsia and its associated risk factors in pregnant women in Auchi and environs. Materials and Methods: In this cross-sectional study, a total number of 200 participants were enrolled. Anthropometric
parameters and blood pressure were measured by standard procedures. 5 ml of blood was obtained from each participant. Serum obtained from the centrifugation of the blood was used for the determination of creatinine, uric acid, alanine aminotransferase, aspartate aminotransferase, and lipid profile. Analysis of data was done using analysis of variance and Pearson correlation coefficient. Statistical significance was set at P ≤ 0.05. Results: The prevalence of preeclampsia in this study was 4%. Body mass index, waist circumference, serum creatinine, uric acid, and total cholesterol (TC) were significantly elevated in pregnant women with preeclampsia in comparison with women without preeclampsia. Conclusion: Observations in this study indicate that elevated serum creatinine, uric acid, and TC are risk factors of preeclampsia.

 

Pages 75-80
Year 2025
Issue 2
Volume 9

Download

Posted by Basem

msp.02.2025.68.74

ENHANCING ANTICANCER PROPERTIES OF ORGANOSULFUR COMPOUNDS IN ALLIUM CEPA THROUGH NITROGEN, SULFUR, AND POTASSIUM FORTIFICATION IN BARREN LANDS

Journal: Matrix Science Pharma (MSP)
Tariq M. Qureshi, Eesha Tir Raazia, Ahsan, Numra Shehzadi, M. Asif Khan

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited

DOI: 10.4103/mtsp.mtsp_15_24

ABSTRACT

Background: To fortify nutrients depleting loam being waste under murkiness and use it for enhancing anticancer food rationing in the human body, two onions (Allium cepa) cultivars i.e., Cv.1 and Cv.2 (locally called “imported and 144” respectively) were experienced. Aims and Objectives: The objective of this study was to evaluate the growth, yield, and anticancer nutrient potential of two onion cultivars under varying shaded conditions to explore their performance in depleted soils with added essential macronutrients. Materials and Methods: Fertilizers were applied at the rate of 50 kg of NH₄(SO₄)₂ and 25 kg of MOP (muriate of potash) per acre⁻¹ with the first irrigation. Growth parameters were recorded under un-shaded, partially, and fully shaded canopies of Eugenia trees. Results: Maximum weights (162±9 g), horizontal diameters (7.83±0.77 cm), circumferences (24.20±2.4 cm), and number of leaves per plant (15±0.25) of onion bulbs were recorded in Cv.1 under shaded conditions followed by Cv.2 (weight 135±7 g, 7.82±1.01 cm, 22.5±2.2 cm, 14±0.92 respectively). Similarly, the maximum yield of bulbs (small and medium-sized) was 18±0.11 and 8.25±0.55 ton ha⁻¹ in Cv.1 under un-shaded and 17±0.54 and 8.25±0.55 ton ha⁻¹ under partially shaded conditions, while the lowest (6±0.36 ton ha⁻¹) was observed in large-sized bulbs under fully shaded conditions. More sprouting (40±2.1%) was observed under un-shaded, whereas least (18±3.5%) under partially shaded conditions in Cv.1. Conclusion: The
response of both cultivars was beneficial under such an environment; however, Cv.1 was better. It was inferred from the results that onion, which is an excellent source of moderate levels of anticancer diet, can be obtained on these depleted soils by adding essential macronutrients.

 

Pages 68-74
Year 2025
Issue 2
Volume 9

Download

Posted by Basem

msp.01.2025.54.61

SOCIODEMOGRAPHIC, DIETARY, AND LIFESTYLE FACTORS ASSOCIATED WITH OVERWEIGHT AND OBESITY IN SCHOOL CHILDREN IN INDONESIA AND JAMAICA: A COMPARATIVE STUDY

Journal: Matrix Science Pharma (MSP)
Putri Bungsu Machmud, Wahyu Kurnia Putra, Sarah N. Oshi, Chinwendu F. Agu, Magdalene Nwokocha, Nurul Khairani, Chukwuemeka R. Nwokocha, Daniel C. Oshi

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited

DOI: 10.4103/mtsp.mtsp_23_24_1

ABSTRACT

Background: Childhood obesity is on the increase in many developing countries and constitutes a major public health problem. Aim and Objectives: This study sought to investigate the prevalence and factors associated with overweight and obesity in school children in Indonesia and Jamaica. Materials and Methods: We conducted the descriptive and inferential analyses of two large datasets obtained from the Global School-based Health Survey 2015 in Indonesia and 2017 in Jamaica. Multinomial logistic regression modeling was used to assess factors associated with overweight and obesity. Results: The prevalence of overweight and obesity was higher in Jamaican students (13.5% and 10.4%, respectively) than in Indonesian students (11% and 5.2%, respectively). There were also disparities in the strength and direction of the associations between the explanatory variables and overweight and obesity in the two countries. Age, gender, consumption of fruits, tobacco smoking, physical activity, and alcohol consumption were significantly associated with overweight and obesity. Conclusion: The findings suggest that policy‑makers and planners of programs for the prevention and control of childhood overweight and obesity should take age, gender, dietary factors, and lifestyles into consideration within the specific contexts of their country.

 

Pages 54-61
Year 2025
Issue 1
Volume 9

Download

Posted by Basem

msp.01.2025.49.53

INJURY OF RECURRENT LARYNGEAL NERVE IN THYROID SURGERY: A SCOPING REVIEW

Journal: Matrix Science Pharma (MSP)
Santosh Kumar Swain

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited

DOI: 10.4103/mtsp.mtsp_31_24_1

ABSTRACT

Thyroid surgery is a common surgical procedure in routine surgical practice. Recurrent laryngeal nerve (RLN) injury is an important reason for medical disputes from thyroid surgery. One of the most feared complications of thyroid surgery is vocal cord paralysis brought on by RLN damage. Injury of RLN with vocal cord palsy is a complication of thyroidectomy that profoundly affects patients. Patients are severely disabled as a result, both mentally and physically. Even though RLN injuries are rare, they might compromise one’s quality of life. Asignificant clinical condition known as bilateral RLN damage occurs when both vocal cords assume the median or paramedian position, obstructing the airway and necessitating an immediate tracheostomy. Identification and preservation of nerves depend on intraoperative hemostasis and a thorough knowledge of RLN anatomy. Injury of RLN following thyroid surgery is one of the leading causes of medico‑legal litigation against the operating surgeon. Early identification of RLN injuries and appropriate management are crucial to prevent these surgical complications.

 

Pages 49-53
Year 2025
Issue 1
Volume 9

Download

Posted by Basem

msp.04.2024.85.86

AYURVEDA AND HIGH URIC ACID

Journal: Matrix Science Pharma (MSP)
Letter to Editor

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited

DOI: 10.4103/mtsp.mtsp_11_24_1

ABSTRACT

High levels of uric acid in the body are called hyperuricemia. Hyperuricemia occurs when uric acid forms faster than it eliminates from the body. Uric acid saturates body fluids leading to formation and accumulation of monosodium urate monohydrate crystals in different parts of the body, which manifests in the form of various diseases. Depending on the tissue involved, excess uric acid crystals may cause gout (vatarakta) or urinary calculi (ashmari). Gout can cause joint pain as well as swelling problems that can lead to arthritis. It occurs due to accumulation of urate crystals in joints, tendons, and the surrounding tissues. Urinary calculi are characterized by the accumulation of stones in the urinary system (obstructing the passage of urine) and pain during urination.

 

Pages 85-86
Year 2024
Issue 4
Volume 8

Download

Posted by Basem

msp.04.2024.79.84

CARDIAC PROFILE IN PATIENTS WITH SNAKE ENVENOMATION AND ITS COMPLICATIONS: A RETROSPECTIVE STUDY FROM A TERTIARY CARE CENTER IN SOUTH INDIA

Journal: Matrix Science Pharma (MSP)
Amit Mandal, Ramya Iyyadurai

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited

DOI: 10.4103/mtsp.mtsp_1_24_1

ABSTRACT

Background: Snakebites continue to be a major public health concern throughout the world, and more in tropical countries. Cardiac implications are poorly understood due to the low frequency of cardiotoxicity combined with a lack of robust information. Aims: We aim to study the cardiac profile, complications in snake bite patients requiring admission in a medical unit. Materials and Methods: This retrospective study was conducted carried out from 01/05/2016 to 01/05/2021. The data was extracted from the inpatient medical records and it was analyzed. All adult patients requiring admission in a Medicine unit with a diagnosis of snake envenomation were included. Descriptive statistics were obtained for all variables in the study and appropriate statistical tests were employed to ascertain the significance. Result: The cohort consists of 80 patients with 45(56.3%) males and aged 40.06 ± 15.24 years (mean, SD). The majority of the Snake species identification was not available 38(47.5%). Viper bite was the commonest bite 32 (40%). The commonest clinical presentation was hemotoxic 33 (31.3%) followed by neurotoxic 16(20%). Electrocardiogram abnormalities were seen in 23 (28.7%) patients and commonest abnormality noted was sinus tachycardia 34(42.5%) of cases. 69 (86%) patients had cellulitis and 16(20%) had acute kidney injury (AKI). Twenty-four (30%) required intensive care monitoring, 22 (27.5%) required mechanical ventilation and 7 (8.8%) patients required hemodialysis. The mean ± SD duration of hospital stay was of 5.56 ± 3.76 days. The median direct cost was Rs 19714.5 and cost on medicine was Rs 10798. The mortality in this cohort was 4(5%). Conclusion: Snake bite causes significant morbidity. Viper bite was the commonest bite in our study. The mortality in this cohort was 4(5%). Cardiac toxicity is a clearly defined toxicity following snake bite envenomation however it has no effect on mortality

 

Pages 79-84
Year 2024
Issue 4
Volume 8

Download

Posted by Basem

msp.04.2024.70.78

KNOWLEDGE, ATTITUDES, AND PRACTICES OF MOTHERS WITH ACUTELY MALNOURISHED CHILDREN REGARDING CHILD FEEDING AND MALNUTRITION PREVENTION IN SUDAN

Journal: Matrix Science Pharma (MSP)
Hind S. Haran, Abdelrahim M. Elameen, Yasir A. M. Eltahir, Ahmed H. Arbab

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited

DOI: 10.4103/mtsp.mtsp_26_23_1

ABSTRACT

Background: Malnutrition remains a global health issue, endangering the lives of millions of children, especially in developing nations. It profoundly affects a child’s physical and mental development, leading to severe and often irreversible consequences. Objectives: This study aims to assess the knowledge, attitudes, and practices of mothers with acutely malnourished children concerning child feeding and the prevention of malnutrition. Subjects and Methods: A cross‑sectional hospital‑based study was conducted involving 139 mothers with acutely malnourished children admitted to the malnutrition ward at Mohammed Al‑Ameen Hamid Pediatric Hospital between May 2022 and December 2022. Data were collected through direct interviews with the surveyed mothers utilizing a validated, structured questionnaire. Analysis of data was performed using SPSS software version 20. Results: The study revealed that 78.4% of mothers possessed adequate knowledge, 80.6% exhibited favorable attitudes, and 55.4% demonstrated good child‑feeding practices and malnutrition prevention practices. A significant correlation between mothers’ education and practice was identified (P = 0.025). Furthermore, data analysis highlighted the significant association between mothers’ knowledge and attitude (P = 0.007), mothers’ knowledge and practice (P = 0.006), and mothers’ attitudes and practice (P = 0.033). Conclusion: Most mothers exhibited sufficient knowledge and positive attitudes regarding child feeding and malnutrition prevention; however, there is a need to translate this awareness into improved practices.

 

Pages 70-78
Year 2024
Issue 4
Volume 8

Download

Posted by Basem

msp.04.2024.65.69

IMPACT OF ROLE MODELS ON MEDICAL STUDENTS

Journal: Matrix Science Pharma (MSP)
Santosh Kumar Swain

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited

DOI: 10.4103/mtsp.mtsp_18_24_1

ABSTRACT

Role modeling plays an important role in the theoretical and practical background of medical education. The vital function of role modeling includes humanism and professionalism in medical education. The use of teaching faculties as role models for professional aspects of medical students is a need of the hour. The transformation of medical students to medical professionals is an important core competency needed for becoming expert clinicians in the current century. Role modeling is a key method for transmitting this professional skill among medical students. The professionalism of medical students is best learned through role models. The National Medical Commission in India is developing medical curriculum which ensures the students for development of professional competency and understanding values in medical education. The most important qualities in role models are a positive attitude toward junior colleagues, compassion for patients, and integrity. Students assess their clinical teachers not only on their clinical or practical skills but also on their soft skills. Role models facilitate the learning of the medical students and assist in the development of professional identity. However, social organization and cultural values influence the choice of role models. Excellence in role modeling entails the demonstration of excellent patient care, teaching skills, and personal values/characteristics. The aim of this review is to discuss on the student perception of professionalism with role models in medical school.

 

Pages 65-69
Year 2024
Issue 4
Volume 8

Download

Posted by Basem

msp.03.2024.62.64

NICOTINAMIDE RIBOSIDE: AN UPDATE

Journal: Matrix Science Pharma (MSP)
Letter to Editor

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited

DOI: 10.4103/mtsp.mtsp_10_24_1

ABSTRACT

Nicotinamide riboside (NR) is a form of Vitamin B3 (niacin) and a precursor to nicotinamide adenine dinucleotide (NAD+), a vital coenzyme found in all living cells.[1] NAD+ is involved in various metabolic processes, including energy production, DNA repair, and cell signaling. NR has gained attention for its possible health benefits, such as enhancing brain health, improving mitochondrial function, and promoting healthy aging. It is offered as a dietary supplement and is being studied for its potential therapeutic applications. NR can exist in both amorphous and crystalline forms, depending on how it is processed and formulated. The crystalline form is typically more stable and easier to characterize, which is advantageous for manufacturing and quality control in supplement production. On the other hand, the amorphous form can sometimes offer better bioavailability and solubility, although it may be less stable over time. Manufacturers may choose the form of NR based on desired product characteristics, such as stability, solubility, and ease of incorporation into different supplement forms (capsules, tablets, powders, etc.).

 

Pages 62-64
Year 2024
Issue 3
Volume 8

Download

Posted by Basem