PHYTOCHEMICAL ANALYSIS, PEPTIC ULCER CURATIVE, ANTIOXIDANT AND
MEMBRANE STABILIZATION POTENTIAL OF THE EXTRACT OF CALLITRIS ROBUSTA VAR. MICROCARPA
Journal: Matrix Science Pharma (MSP)
Authors: Zacchaeus S. Ololade,Bolarinde O. Olugboye,Olayinka F. Onifade,Olawumi T. Oyebanji,Temidayo E. Alabi
This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited
DOI: 10.26480/msp.03.2026.79.90
ABSTRACT
Callitris robusta var. microcarpa (CRM) contains phytochemicals used to treat diverse ailments, and this study investigated its antioxidant phytochemicals for curative effects on various gastrointestinal disorders using chromatographic and multifaceted biochemical assays, showing that CRM provides better gastrointestinal protection and ulcer healing potential compared with cimetidine, significantly reduces ulcer scores, maintains stomach mucosa integrity by minimizing oxidative damage through reduction of ROS levels, demonstrates viable muscularis-propria wall mucosal lining cells without abnormalities in histological screening, increases membrane stability suggesting reinforcement of membrane integrity, and provides evidence of its therapeutic use as a natural antioxidant for gastrointestinal protection.
| Pages | 79-90 |
| Year | 2025 |
| Issue | 3 |
| Volume | 10 |
